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1

Modelling Learning and Memory in Drosophila to Understand Intellectual Disabilities

Mariano, Vittoria, Achsel, Tilmann, Bagni, Claudia, Kanellopoulos, Alexandros K.

Journal:

Year:

2020

File:

PDF, 2.17 MB

2020

2

Deficient brain snRNP70K in patients with Down syndrome

Rainer Seidl, Olga Labudova, Kurt Krapfenbauer, Elisabeth Welin Henriksson, Joe Craft, Dritan Turhani-Schatzmann, Tilmann Achsel, Bettina Bidmon, GJM Pruijn, Nigel Cairns, Gert Lubec

Journal:

ELECTROPHORESIS

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

3

Superoxide dismutase 1 modulates expression of transferrin receptor

Ruth Danzeisen, Tilmann Achsel, Ulrich Bederke, Mauro Cozzolino, Claudia Crosio, Alberto Ferri, Malte Frenzel, Edith Butler Gralla, Lea Huber, Albert Ludolph, Monica Nencini, Giuseppe Rotilio, Joan Se

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2006

Language:

english

File:

PDF, 364 KB

english, 2006

4

Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration

Alessia Maracchioni, Antonio Totaro, Daniela F. Angelini, Alessandra Di Penta, Giorgio Bernardi, Maria Teresa Carrì, Tilmann Achsel

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 678 KB

english, 2007

5

RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies

Schaffert, Nina, Hossbach, Markus, Heintzmann, Rainer, Achsel, Tilmann, Lührmann, Reinhard

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 379 KB

english, 2004

6

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

Journal:

The EMBO Journal

Year:

1999

Language:

english

File:

PDF, 614 KB

english, 1999

7

mRNPs, polysomes or granules: FMRP in neuronal protein synthesis

Francesca Zalfa, Tilmann Achsel, Claudia Bagni

Journal:

Current Opinion in Neurobiology

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

8

The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions

Evgeny M Makarov, Olga V Makarova, Tilmann Achsel, Reinhard Lührmann

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 397 KB

english, 2000

9

The fragile X mental retardation protein–RNP granules show an mGluR-dependent localization in the post-synaptic spines

Francesca Ferrari, Valentina Mercaldo, Giovanni Piccoli, Carlo Sala, Stefano Cannata, Tilmann Achsel, Claudia Bagni

Journal:

Molecular and Cellular Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.85 MB

english, 2007

10

Coupled In Vitro Import of U snRNPs and SMN, the Spinal Muscular Atrophy Protein

Usha Narayanan, Tilmann Achsel, Reinhard Lührmann, A.Gregory Matera

Journal:

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

11

Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm

Gerbino, Valeria, Carrì, Maria Teresa, Cozzolino, Mauro, Achsel, Tilmann

Journal:

Neurobiology of Disease

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

12

The Human U5-200kD DEXH-Box Protein Unwinds U4/U6 RNA Duplices in vitro

Bernhard Laggerbauer, Tilmann Achsel and Reinhard Luhrmann

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.43 MB

english, 1998

13

Dendritic LSm1/CBP80-mRNPs Mark the Early Steps of Transport Commitment and Translational Control

Alessandra di Penta, Valentina Mercaldo, Fulvio Florenzano, Sebastian Munck, M. Teresa Ciotti, Francesca Zalfa, Delio Mercanti, Marco Molinari, Claudia Bagni and Tilmann Achsel

Journal:

The Journal of Cell Biology

Year:

2009

Language:

english

File:

PDF, 2.87 MB

english, 2009

14

Identity elements of human tRNA Leu : structural requirements for converting human tRNA Ser into a leucine acceptor in vitro

Breitschopf, Kristin, Achsel, Tilmann, Busch, Kristina, Gross, Hans J.

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 556 KB

english, 1995

15

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

Papadopoulou, Aikaterini S., Serneels, Lutgarde, Achsel, Tilmann, Mandemakers, Wim, Callaerts-Vegh, Zsuzsanna, Dooley, James, Lau, Pierre, Ayoubi, Torik, Radaelli, Enrico, Spinazzi, Marco, Neumann, Me

Journal:

Neurobiology of Disease

Year:

2015

Language:

english

File:

PDF, 4.19 MB

english, 2015

16

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry

La Fata, Giorgio, Gärtner, Annette, Domínguez-Iturza, Nuria, Dresselaers, Tom, Dawitz, Julia, Poorthuis, Rogier B, Averna, Michele, Himmelreich, Uwe, Meredith, Rhiannon M, Achsel, Tilmann, Dotti, Carl

Journal:

Nature Neuroscience

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

17

Neuronal RNA-binding proteins in health and disease

Lenzken, Silvia Carolina, Achsel, Tilmann, Carrì, Maria Teresa, Barabino, Silvia M.L.

Journal:

Wiley Interdisciplinary Reviews: RNA

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

18

Molecular dynamics simulations show how the FMRP Ile304Asn mutation destabilizes the KH2 domain structure and affects its function

Di Marino, Daniele, Achsel, Tilmann, Lacoux, Caroline, Falconi, Mattia, Bagni, Claudia

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

19

The Sm domain is an ancient RNA-binding motif with oligo(U) specificity

Achsel, T., Stark, H., Luhrmann, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 308 KB

english, 2001

20

Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS

Rossi, S., Serrano, A., Gerbino, V., Giorgi, A., Di Francesco, L., Nencini, M., Bozzo, F., Schinina, M. E., Bagni, C., Cestra, G., Carri, M. T., Achsel, T., Cozzolino, M.

Journal:

Journal of Cell Science

Year:

2015

Language:

english

File:

PDF, 2.55 MB

english, 2015

21

BC1-FMRP interaction is modulated by 2'-O-methylation: RNA-binding activity of the tudor domain and translational regulation at synapses

Lacoux, C., Di Marino, D., Pilo Boyl, P., Zalfa, F., Yan, B., Ciotti, M. T., Falconi, M., Urlaub, H., Achsel, T., Mougin, A., Caizergues-Ferrer, M., Bagni, C.

Journal:

Nucleic Acids Research

Year:

2012

Language:

english

File:

PDF, 6.44 MB

english, 2012

22

The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

Paronetto, M. P., Achsel, T., Massiello, A., Chalfant, C. E., Sette, C.

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 3.08 MB

english, 2007

23

The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique

Totaro, A., Renzi, F., La Fata, G., Mattioli, C., Raabe, M., Urlaub, H., Achsel, T.

Journal:

Nucleic Acids Research

Year:

2011

Language:

english

File:

PDF, 5.23 MB

english, 2011

24

MD and Docking Studies Reveal That the Functional Switch of CYFIP1 is Mediated by a Butterfly-like Motion

Di Marino, Daniele, Chillemi, Giovanni, De Rubeis, Silvia, Tramontano, Anna, Achsel, Tilmann, Bagni, Claudia

Journal:

Journal of Chemical Theory and Computation

Year:

2015

Language:

english

File:

PDF, 8.07 MB

english, 2015

25

Fragile X Mental Retardation Protein (FMRP) Binds Specifically to the Brain Cytoplasmic RNAs BC1/BC200 via a Novel RNA-binding Motif

Zalfa, F., Adinolfi, S., Napoli, I., Kuhn-Holsken, E., Urlaub, H., Achsel, T., Pastore, A., Bagni, C.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 497 KB

english, 2005

26

Dendritic LSm1/CBP80-mRNPs mark the early steps of transport commitment and translational control

di Penta, A., Mercaldo, V., Florenzano, F., Munck, S., Ciotti, M. T., Zalfa, F., Mercanti, D., Molinari, M., Bagni, C., Achsel, T.

Journal:

The Journal of Cell Biology

Year:

2009

Language:

english

File:

PDF, 5.41 MB

english, 2009

27

FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression

Fernandez, E., Li, K. W., Rajan, N., De Rubeis, S., Fiers, M., Smit, A. B., Achsel, T., Bagni, C.

Journal:

Journal of Neuroscience

Year:

2015

Language:

english

File:

PDF, 891 KB

english, 2015

28

The RNA-Binding Protein Sam68 Modulates the Alternative Splicing of Bcl-x

Maria Paola Paronetto, Tilman Achsel, Autumn Massiello, Charles E. Chalfant and Claudio Sette

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.68 MB

english, 2007

29

Factors Involved in the Activation of Pre-mRNA Splicing from Downstream Splicing Enhancers

Achsel, T., Shimura, Y.

Journal:

Journal of Biochemistry

Year:

1996

Language:

english

File:

PDF, 5.53 MB

english, 1996

30

Cooperativity in RNA–protein interactions: the complex is more than the sum of its partners

Achsel, Tilmann, Bagni, Claudia

Journal:

Current Opinion in Neurobiology

Year:

2016

Language:

english

File:

PDF, 417 KB

english, 2016

31

The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free Complex with Several U5-Specific Proteins, Including an RNA Unwindase, a Homologue of Ribosomal Elongation Factor EF-2, and a Novel WD-40 Protein

Achsel, Tilmann, Ahrens, Katharina, Brahms, Hero, Teigelkamp, Stefan, Lührmann, Reinhard

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 3.29 MB

english, 1998

32

Sm-like proteins in the pathogenesis of Spinal Muscular Atrophy

Tilmann Achsel,Robin Doms,Claudia Bagni,Fabrizio Renzi

Journal:

Year:

2015

Language:

english

File:

PDF, 580 KB

english, 2015

33

The fragile X mental retardation protein (FMRP) expression is associated with better distant metastasis free survival in a cohort of luminal-B like early breast cancers with long follow-up

Floris, G., Piedini, G., Laenen, A., Van Asten, K., Achsel, T., Brouckaert, O., Wildiers, H., Bagni, C., Neven, P.

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 50 KB

english, 2018

34

The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

Laggerbauer, B., Achsel, T., Luhrmann, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 288 KB

english, 1998

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